Micky van de Ven Brace Ends The Toffees' Run at New Home Ground
The Dutch defender emerged as the first defender to score two goals in a Premier League game for Tottenham since the Belgian defender in spring 2013.
Match summary
The Spurs defender nods home twice in opening period
The home side's defender has equalizer ruled after video check
Senegalese midfielder nets final goal in dying moments
The defeat is the Merseyside club's first at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Tottenham extended their winning streak in away games in the top division and handed Everton their first defeat at their new home.
Everton were undefeated in their five previous fixtures at their new ground at Bramley-Moore Dock, having departed their historic home behind after more than a century at the end of last season.
But Spurs captain Van de Ven struck on two occasions from set-pieces in the first half to place their impressive record at risk, and they were unable to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward Richarlison - nodded in a final goal to seal the victory.
The Everton defender thought he had equalized the tally a short while after the defender's first goal, glancing a bullet header past Guglielmo Vicario from an Everton corner.
The Portuguese striker, meanwhile, missed a handful of opportunities, while the Italian goalkeeper made a succession of fine stops to guarantee the London club went five away games without defeat in the English top flight.
But the VAR intervened, instructing Craig Pawson to review the score on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had impeded with the Tottenham goalkeeper.
This victory moves Thomas Frank's team up to third in the division, five points off local foes and table-toppers Arsenal.
Everton stay 14th and sit six points clear of the relegation zone.
Spurs breakdown: Van de Ven excels in duties at each end of pitch
Following a uninspiring midweek performance in the Champions League against the French side, where they mustered a mere attempts on goal, the manager chose the French striker in attack instead of ex-Everton forward Richarlison.
The new arrival was unable to influence the game before being replaced for the substitute after 60 minutes on the field, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an offensive threat to be reckoned with.
Tottenham's first goal came from a well-worked set-piece play, with Rodrigo Bentancur directing the ball toward the six-yard box for an unmarked the defender to score.
And Ven de Ven - stepping up as skipper in Cristian Romero's unavailability - notched his next goal in added time as he rose above Jordan Pickford to head home.
The Dutchman was equally outstanding in defensive duties, combining effectively with Kevin Danso as the duo dealt excellently with the 34 crosses thrown their way by the opposition.
Toffees breakdown: Toffees missing finishing touch
The club's recent stadium had been a happy hunting ground, but it appears the freshness may have faded somewhat and supporters headed to the gates after the midfielder's final goal for Tottenham.
The end in Everton's winning streak at home won't be a major concern for the manager, but their striker situation are.
Beto and Thierno Barry - the Everton's pair of established centre-forwards - had scored only one league goal between them before Sunday's outing.
And they were unable to contribute to that miserable tally on a wet and gloomy night on in Liverpool.
The striker's performance was summed up when he chose to overhead kick a clear chance from near the goal, despite having room and opportunity to reposition for a simpler attempt that would have challenged Vicario.
Barry, as well, was unable to make an impact after replacing Beto in the second half.
It wasn't for a shortage of chance. Most of the home side's attacks came through the winger and Ndiaye, who tirelessly whipped threatening crosses into the Spurs box.
What next for both teams?
Everton: Moyes' men head to the Stadium of Light in the top flight on Monday, 3 November at 8 PM.
Spurs: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup match against the Magpies.